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Modern drug therapy for ED made a significant advance in 1983, when British physiologist Giles Brindley, Ph.D. dropped his trousers and demonstrated to a shocked Urodynamics Society audience his papaverine-induced erection. The drug Brindley injected into his penis was a non-specific vasodilator, an alpha-blocking agent, and the mechanism of action was clearly corporal smooth muscle relaxation. The effect that Brindley discovered established the fundamentals for the later development of specific, safe, orally effective drug therapies.[better source needed][better source needed] How Is Male Sexual Dysfunction Treated? Many cases of sexual dysfunction can be corrected by treating the underlying physical or psychological problems. Treatment strategies may include the following: Mechanical aids: Aids such as vacuum devices and penile implants may help men with erectile dysfunction. There have been rare reports of priapism (prolonged and painful erections lasting more than six hours) with the use of oral PDE5 inhibitors such as vardenafil, sildenafil, and tadalafil. Men with blood cell diseases such as sickle cell anemia, leukemia, and multiple myeloma have higher than normal risks of developing priapism. Untreated priapism can cause injury to the penile tissue and lead to permanent loss of potency. If there is prolonged erection (longer than four hours), immediate medical assistance should be sought. Real viagra How does an erection normally occur? The cGMP is soon converted into another inactive chemical. But, as you remain sexually aroused whilst having sex, your brain keeps sending nerve messages to the penis which makes more cGMP to maintain the erection. When the level of cGMP falls, the blood flow to the penis returns to normal, and the penis gradually returns to the non-erect state. Medications for erectile dysfunction include: oral phosphodiesterase type 5 (PDE5) inhibitors (sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) Surgery (radiation therapy, surgery of the colon, prostate, bladder, or rectum may damage the nerves and blood vessels involved in erection. Prostate and bladder cancer surgery often require removing tissue and nerves surrounding a tumor, which increases the risk for impotence) buy levitra 20 mg online levitra online
So, even if the nerves or blood vessels going to your penis are not working so well, a tablet can cause the blood flow to increase in your penis, and cause an erection. Tablets can treat ED caused by various underlying conditions. Note: none of these tablets will cause an erection unless you are sexually aroused.